RT Journal Article
T1 Body composition analysis and handgrip strength as predictors of 12-month mortality in hospitalized adults receiving parenteral nutrition: A descriptive cohort study
A1 Montero Madrid, Natalia
A1 Rodríguez Juárez, Raúl
A1 Fernández‐Jiménez, Rocío
A1 Vidal Suárez, Alvaro
A1 Guirado Peláez, Patricia
A1 Martín‐Fontalba, Maria Angeles
A1 Fernández Medina, Beatriz
A1 Vegas Aguilar, Isabel
A1 Amaya Campos, Maria del Mar
A1 Simón Frapolli, Victor
A1 Zarco Martín, Maria Teresa
A1 Tinahones-Madueño, Francisco José
A1 Maria Luisa Fernández Soto, 
A1 García-Almeida, José Manuel
K1 Enfermos - Nutrición
AB BackgroundNutrition assessment in patients receiving parenteral nutrition often relies on classical parameters with limited prognostic value. Morphofunctional tools such as phase angle and handgrip strength measurement offer a more comprehensive evaluation of nutrition status and may better predict clinical outcomes.ObjectiveTo evaluate the predictive value of phase angle and handgrip strength for 12-month mortality in hospitalized patients receiving parenteral nutrition.MethodsA retrospective observational study was conducted in 614 patients treated with parenteral nutrition. Anthropometric assessments were realized. Morphofunctional assessments included bioelectrical impedance analysis to determine phase angle and dynamometry to measure handgrip strength. Survival analysis was performed using Cox proportional hazards models and Kaplan-Meier curves and cutoff values by receiver operating characteristic curve analysis.ResultsSix hundred fourteen patients received parenteral nutrition, with a mean age of 64 ± 14.6 years; 58.2% were male. After 1 year, the mortality rate was 26.1%, and the average hospital stay was 27.9 ± 23.8 days. Twelve-month survival was reduced in patients with low phase angle (57%) and low handgrip strength (62.8%) compared with those with preserved values (84% and 82.2%, respectively). In the multivariable logistic regression model adjusted for age, sex, and body mass index, each unit increase in phase angle and handgrip strength was associated with a 4% and 2% reduction in mortality odds, respectively (phase angle: odds ratio [OR], 0.6; 95% CI, 0.5–0.7; P < 0.001; handgrip strength: OR, 0.9; 95% CI, 0.9–1.0; P = 0.03624).ConclusionPhase angle and handgrip strength are predictors of 12-month mortality in patients receiving parenteral nutrition.
PB Wiley
YR 2026
FD 2026-03-05
LK https://hdl.handle.net/10630/46019
UL https://hdl.handle.net/10630/46019
LA eng
NO Madrid NM, Juárez RR, Fernández-Jiménez R, et al. Body composition analysis and handgrip strength as predictors of 12-month mortality in hospitalized adults receiving parenteral nutrition: a descriptive cohort study. J Parenter Enteral Nutr. 2026; 1-9. doi:10.1002/jpen.70069
NO Funding for open access charge: Universidad de Málaga / CBUA
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 21 mar 2026