RT Journal Article
T1 Understanding menstrual blood-derived stromal/stem cells: Definition and properties. Are we rushing into their therapeutic applications?
A1 Sánchez-Mata, Alicia
A1 González-Muñoz, María Elena
K1 Células madre
K1 Menstruación
K1 Células sanguíneas
K1 Sangre
K1 Medicina regenerativa
AB Cells with mesenchymal stem cell properties have been identified in menstrual blood and termed menstrual blood-derived stem/stromal cells (MenSCs). MenSCs have been proposed as ideal candidates for cell-based therapy in regenerative medicine and immune-related diseases. However, MenSCs identity has been loosely defined so far and there is controversy regarding their cell markers and differentiation potential. In this review, we outline the origin of MenSCs in the context of regenerating human endometrium, with attention to endometrial eMSCs as reference cells to understand MenSCs. We summarize the cell identity markers analyzed and the immunomodulatory and reparative properties reported. We also address the recent use of MenSCs in cell reprogramming. The main goal of this review is to contribute to the understanding of the identity and properties of MenSCs as well as to identify potential caveats and new venues that deserve to be explored to strengthen their potential applications.
PB CellPress
YR 2021
FD 2021-12-17
LK https://hdl.handle.net/10630/38818
UL https://hdl.handle.net/10630/38818
LA eng
NO Alicia Sanchez-Mata, Elena Gonzalez-Muñoz, Understanding menstrual blood-derived stromal/stem cells: Definition and properties. Are we rushing into their therapeutic applications?, iScience, Volume 24, Issue 12, 2021, 103501, ISSN 2589-0042, https://doi.org/10.1016/j.isci.2021.103501
NO MINECO-SAF2015-66105-R, RYC-2014-15410,UMA18-FEDERJA-107
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 4 mar 2026