RT Conference Proceedings
T1 Overrepresentation of verbal repetition deficits in aphasic men with stroke: A systematic literature review and meta-analysis
A1 Torres-Prioris, María José
A1 Pertierra, Lucía
A1 Dávila-Arias, María Guadalupe
A1 Allegri, Ricardo F
A1 López-Barroso, Diana
A1 Berthier-Torres, Marcelo Luis
K1 Afasia
AB Introduction: The arcuate fasciculus (AF) is a key component for language repetition Neuroimaging evidenceindicates a gender-dimorphic architecture of this white matter tract. Strong left lateralization of the directsegment of the AF is m∼ore frequent in men ( 85%), while mild lateralization or symmetrical bilateral∼ representation ( 60%) is more prevalent amongst women. Therefore, most men do not have a well-developedright AF. This predicts that men with aphasia and left hemisphere damage will have less capacity than aphasicwomen to compensate repetition deficits and, consequently, aphasias associated to repetition deficits (e.gconduction aphasia – CA) will be more prevalent in men. While this assumption is intuitively appealing, it has notbeen empirically tested up to now.Methods: A systematic review and meta-analysis of published cases of CA and transcortical aphasia (TA) wasperformed. Adult patients with first-ever unilateral cerebrovascular event and no prior history of neurological orpsychiatric disease were included in the database. The men: women proportion of CA and TA was calculatedfrom the database, and compared with the men:women proportion of stroke prevalence. The group of patientswith aphasias showing relatively preserved repetition (transcortical motor and sensory aphasias) was used ascontrol. Patients with mixed transcortical aphasia were excluded because repetition is not fully preserved.Results: Two hundred fifty three publications were included, gathering 799 cases of CA and TA. Malesaccounted for 74% (n = 375) of CA subjects (n = 507), while among TA (n=249, mixed TA excluded) menrepresented 62% (n=154) of subjects. Compared with 59% of male prevalence in stroke, men wereoverrepresented amongst CA (p<0.0001, 95% CI 68.91 to 76.82) in comparison with the control group (TA withexclusion of mixed TA, p= 0.2848, 95% CI 55.50 to 67.91).Discussion:Chronic repetition deficits are more prevalent in men than in women.This finding has importantimplications for the diagnosis and rehabilitation of aphasia in men, since verbal repetition is a major resource inlanguage therapy.References: Catani M et al. PNSA (2007)104(43), 17163-17168.Berthier ML et al. Cortex (2012) 48, 133-143.
YR 2017
FD 2017-02-01
LK http://hdl.handle.net/10630/12850
UL http://hdl.handle.net/10630/12850
LA eng
NO Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 22 ene 2026