RT Journal Article
T1 Neutrophils as indicators of obesity-associated inflammation: a systematic review and meta-analysis.
A1 Gomez-Casado, Gema
A1 Jimenez-Gonzalez, Andrés
A1 Rodríguez-Muñoz, Alba
A1 Tinahones-Madueño, Francisco José
A1 González-Mesa, Ernesto Santiago
A1 Murri, Mora
K1 Obesidad
K1 Neutrófilos
AB Introduction: The aim of this study is to evaluate and compare the suitability of rou-tine blood neutrophil values as indicators of obesity-associated inflammation.Methods: In this systematic review and meta-analysis, we assess absolute neutrophilcounts (ANCs) and neutrophil-to-lymphocyte ratio (NLR) values in subjects with andwithout obesity and analyze the weight of both parameters on the disease. Addition-ally, correlation studies between ANC and NLR with BMI, a parameter internationallyaccepted to define obesity are performed.Results: Quantitative data from 12 (ANC) and 11 (NLR) studies were included, with atotal of 4475 participants. The meta-analysis shows that while both parameters areincreased in the obesity group, ANC values present higher differences with the con-trol and less heterogeneity among studies. Additionally, unlike NLR, ANC demon-strates a positive and significant correlation with BMI.Conclusion: Overall, this meta-analysis demonstrates that ANC is a more reliable andstable parameter than NLR for the assessment of obesity-related inflammation, whichoffers clinicians a novel tool to assist in preventing complications related to obesity
PB Wiley
YR 2024
FD 2024
LK https://hdl.handle.net/10630/35522
UL https://hdl.handle.net/10630/35522
LA eng
NO Gomez-Casado G, Jimenez-Gonzalez A, Rodriguez-Muñoz A, et al. Neutrophils as indicators of obesity-associated inflammation: A systematic review and meta-analysis. Obesity Reviews. 2024;e13868. doi:10.1111/obr.13868
NO Funding for open access charge: Universidad de Málaga / CBUA UMA18-FEDERJA-285/Universidad de MálagaProyExcel_00962/Consejería de Conocimiento, Investigación y Universidad, Junta de AndalucíaCP20/0060/Instituto de Salud Carlos IIICPII22-00013/Instituto de Salud Carlos IIIFI23/00104/Instituto de Salud Carlos IIIPI19/00507/Instituto de Salud Carlos IIIPI22/01813/Instituto de Salud Carlos IIIPI23/00293/Instituto de Salud Carlos IIIC1-0002-2022/Consejería de Salud y Familias, Junta de AndalucíaCB06/03/0018/Consejería de Salud y Familias, Junta de AndalucíaPI-0297-2018/Consejería de Salud y Familias, Junta de AndalucíaPY20-00447/Consejería de Salud y Familias, Junta de Andalucía
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 20 ene 2026