RT Journal Article T1 Growth of Bifidobacterium species is inhibited by free fatty acids and bile salts but not by glycerides. A1 Pérez-Burillo, Sergio A1 Rajakaruna, Sumudu A1 Paliy, Oleg K1 Bacterias gram positivas K1 Ácidos grasos K1 Lípidos K1 Glicéridos K1 Acidos biliares AB High-fat diets have been associated with lower gut and fecal abundances of genusBifidobacterium. Here, we investigated whether commonly consumed dietary free fatty acids haveany detrimental effect on the growth of B. adolescentis, B. bifidum, and B. longum. We found that thepresence of free fatty acids in the medium inhibits the growth of Bifidobacterium species to a varyingdegree, with capric (C10:0), oleic (C18:1), and linoleic (C18:2) acids displaying the largest effect. Incomparison, free fatty acids did not affect the growth of Escherichia coli. When fats were added as amixture of mono- and diacylglycerols, the inhibitory effect on Bifidobacterium growth was abolished. PB AIMS Press YR 2022 FD 2022-02-10 LK https://hdl.handle.net/10630/38625 UL https://hdl.handle.net/10630/38625 LA eng NO Perez-Burillo S, Rajakaruna S, Paliy O. Growth of Bifidobacterium species is inhibited by free fatty acids and bile salts but not by glycerides. AIMS Microbiol. 2022;8:53. DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 20 ene 2026