RT Journal Article T1 Lymphocystis disease virus (LCDV-Sa), polyomavirus 1 (SaPyV1) and papillomavirus 1 (SaPV1) in samples of Mediterranean gilthead seabream A1 Labella Vera, Alejandro Manuel A1 Leiva Rebollo, Rocío A1 Ali, Aleja A1 Borrego-García, Juan José K1 Papilomavirus AB Lymphocystis disease, caused by the iridovirus lymphocystis disease virus (LCDV), ischaracterized by the appearance of tumour-like lesions on the skin of affected animals associatedwith several environmental factors and/or with stress due to the intensive culture conditions of fishfarms. In a previous study, the genomes of a new LCDV species, LCDV-Sa, were detected, togetherwith 2 previously unknown viruses, Sparus aurata papillomavirus 1 (SaPV1) and Sparus auratapolyomavirus 1 (SaPyV1). Gilthead seabream from 17 fish farms in Spain, Italy and Turkey weresampled between 2009 and 2015 to investigate the role of the newly described SaPV1 and SaPyV1viruses in lymphocystis disease development. Our results show that in diseased fish, either or bothof the new viruses are almost invariably detected together with LCDV (98%). In asymptomaticfish, these viruses were detected in a much lower percentage (28%) and mostly in concurrencewith LCDV (24%). These data confirm the suspected association among the 3 different virusesduring lymphocystis disease development in gilthead seabream and warrant future studies toestablish their respective contributions. PB Inter-Research Science Publisher YR 2019 FD 2019-01-10 LK https://hdl.handle.net/10630/34083 UL https://hdl.handle.net/10630/34083 LA eng NO Labella AM, Leiva-Rebollo R, Alejo A, Castro D, Borrego JJ (2019) Lymphocystis disease virus (LCDV-Sa), polyomavirus 1 (SaPyV1) and papillomavirus 1 (SaPV1) in samples of Mediterranean gilthead seabream. Dis Aquat Org 132:151-156. https://doi.org/10.3354/dao03311 DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 25 ene 2026