RT Journal Article
T1 Capturing the value of vaccination within health technology assessment and health economics: Literature review and novel conceptual framework
A1 Beck, Ekkehard
A1 Biundo, Eliana
A1 Devlin, Nancy
A1 Doherty, T. Mark
A1 García-Ruiz, Antonio J.
A1 Postma, Maarten
A1 Sheikh, Shazia
A1 Smela, Beata
A1 Toumi, Mondher
A1 Wasem, Jurgen
A1 Nolan, Terry
A1 Salisbury, David
K1 Vacunación
K1 Economía de la salud
AB The objective of this analysis was to focus on health technology assessment systems to identify relevant value concepts in order to improve current EE of non-pandemic vaccines.Methods: Following a literature review, a novel Value of Vaccination (VoV) framework was developed with experts in vaccine EE from developed countries with established health technology assessment systems.Results: Forty-four studies presenting value frameworks or concepts applicable to vaccination were included. Eighteen unique value concepts relevant to EE were identified and defined. These were categorised within the VoV framework using three dimensions, moving from a narrow payer perspective to a more expansive and societal perspective. The dimensions were: (I) conventional payer perspective concepts (e.g., health gains in vaccinees, direct medical costs); (II) conventional societal perspective concepts (e.g., indirect health/economic gains to caregivers/households, productivity in vaccinees); and (III) novel societal concepts (e.g., financial risk protection, peace of mind, societal health gains, healthcare systems security, political stability, social equity and macroeconomic gains). While good quality evidence and methods are available to support concepts in Dimensions I and II, further work is needed to generate the required evidence for vaccination impact on Dimension III concepts.Conclusions: The devastating effect on nations of the COVID-19 pandemic has helped to highlight the potential far-reaching benefits that many vaccination programmes can offer. This VoV framework is particularly relevant to policy decisions considering EE, and the potential future expansion of non-pandemic vaccination value considerations. The framework helps to understand and compare current value considerations across countries and payer versus societal perspectives. It provides decision-makers with atransparent and logical path to broaden consideration of VoV in EE.
PB Elsevier
YR 2022
FD 2022-05
LK https://hdl.handle.net/10630/30293
UL https://hdl.handle.net/10630/30293
LA eng
NO Beck, E., Biundo, E., Devlin, N., Doherty, T. M., Garcia-Ruiz, A. J., Postma, M., Sheikh, S., Smela, B., Toumi, M., Wasem, J., Nolan, T., & Salisbury, D. (2022). Capturing the value of vaccination within health technology assessment and health economics: Literature review and novel conceptual framework. Vaccine, 40(30), 4008–4016
NO GlaxoSmithKline Biologicals SA funded this study (GSK study identifier: VEO-000022/VEO-000023) and all costs related to the development of the publications.
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 20 ene 2026