RT Conference Proceedings
T1 Unraveling the mode of action of a fungicidal and nematicidal dipeptide produced by Bacillus velezensis UMAF6639.
A1 Vela-Corcía, David
A1 Hierrezuelo, Jesús
A1 Pérez-Lorente, Alicia
A1 De-Vicente-Moreno, Antonio
A1 Pérez-García, Alejandro
A1 Romero-Hinojosa, Diego Francisco
K1 Hongos fitopatógenos - Control
K1 Nematodos fitoparásitos - Control
K1 Agentes de control biológico de plagas
AB Unraveling the mode of action of a nematicidal and fungicidal dipeptide produced by Bacillus velezensis UMAF6639David Vela-Corcía, Jesús Hierrezuelo, Alicia Pérez-Lorente, Antonio de Vicente, Alejandro Pérez García, Diego Romero.Instituto de Hortofruticultura Subtropical y Mediterránea “La Mayora”, Universidad de Málaga Consejo Superior de Investigaciones Científicas (IHSM-UMA-CSIC), Departamento de Microbiología, Universidad de Málaga, 29071, Málaga. E-mail: dvela@uma.es/diego_romero@uma.esIn the last decades, the use of beneficial bacteria has become a promising strategy to combat plant diseases. Previous studies have shown that the Bacillus velezensis UMAF6639 strain had an excellent biocontrol capacity against fungal and bacterial diseases of cucurbits. In addition, it had been observed that it could also be effective against plant parasitic nematodes. Currently, the application of chemical agents remains the most common method for managing and controlling these pathogens. However, due to the increasing concern about environmental and public health safety issues, many highly toxic chemical compounds have been restricted in their use. Therefore, there is an urgent need to develop more environmentally friendly ecological alternatives for controlling these pathogens.Therefore, in this study, the identification, characterization, and mode of action description of a molecule produced by Bacillus velezensis UMAF6639, a cyclic dipeptide, which was demonstrated to have nematicidal and fungicidal activity, was carried out. The results indicated that the activity of this molecule was based on a common mechanism capable of altering the physical characteristics of the pathogens plasma membrane, which is key to the physiology and homeostasis of these organisms. This discovery is important because it provides a basis for the development of new biological control agents that are effective against plant diseases caused by pathogens other than fungi and bacteria.
YR 2023
FD 2023
LK https://hdl.handle.net/10630/27492
UL https://hdl.handle.net/10630/27492
LA eng
NO Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 20 ene 2026