RT Journal Article
T1 Use of a personalised depression intervention in primary care to prevent anxiety: a secondary study of a cluster randomised trial.
A1 Moreno-Peral, Patricia
A1 Conejo-Cerón, Sonia
A1 Luna, Juan de Dios
A1 King, Michael
A1 Nazareth, Irwin
A1 Martín-Pérez, Carlos
A1 Fernández-Alonso, Carmen
A1 Ballesta-Rodríguez, María Isabel
A1 Fernández, Anna
A1 Aiarzagüena, José María
A1 Montón-Franco, Carmen
A1 Bellón-Saameño, Juan Ángel
K1 Trastornos de ansiedad
K1 Depresión mental
K1 Atención primaria
K1 Enfermedades mentales - Prevención
K1 Ensayos clínicos
AB Background In the predictD-intervention, GPs used a personalised biopsychosocial programme to prevent depression. This reduced the incidence of major depression by 21.0%, although the results were not statistically significant.Aim To determine whether the predictD-intervention is effective at preventing anxiety in primary care patients without depression or anxiety.Design and setting Secondary study of a cluster randomised trial with practices randomly assigned to either the predictD-intervention or usual care. This study was conducted in seven Spanish cities from October 2010 to July 2012.Method In each city, 10 practices and two GPs per practice, as well as four to six patients every recruiting day, were randomly selected until there were 26–27 eligible patients for each GP. The endpoint was cumulative incidence of anxiety as measured by the PRIME-MD screening tool over 18 months.Results A total of 3326 patients without depression and 140 GPs from 70 practices consented and were eligible to participate; 328 of these patients were removed because they had an anxiety syndrome at baseline. Of the 2998 valid patients, 2597 (86.6%) were evaluated at the end of the study. At 18 months, 10.4% (95% CI = 8.7% to 12.1%) of the patients in the predictD-intervention group developed anxiety compared with 13.1% (95% CI = 11.4% to 14.8%) in the usual-care group (absolute difference = −2.7% [95% CI = −5.1% to −0.3%]; P = 0.029).Conclusion A personalised intervention delivered by GPs for the prevention of depression provided a modest but statistically significant reduction in the incidence of anxiety.
PB Royal College of General Practitioners
YR 2021
FD 2021-01-28
LK https://hdl.handle.net/10630/39009
UL https://hdl.handle.net/10630/39009
LA eng
NO Moreno-Peral, P., Conejo-Cerón, S., de Dios Luna, J., King, M., Nazareth, I., Martín-Pérez, C., Fernández-Alonso, C., Ballesta-Rodríguez, M. I., Fernández, A., Aiarzaguena, J. M., Montón-Franco, C., & Bellón, J. Á. (2021). Use of a personalised depression intervention in primary care to prevent anxiety: a secondary study of a cluster randomised trial. The British journal of general practice : the journal of the Royal College of General Practitioners, 71(703), e95–e104. https://doi.org/10.3399/bjgp20X714041
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 19 ene 2026