RT Conference Proceedings T1 Use of oligonucleotides for the control of Botrytis cinerea in horticultural crops. A1 López-Laguna, Alba A1 Vielba-Fernández, Alejandra A1 Pérez-García, Alejandro A1 Fernández-Ortuño, Dolores K1 Plantas - Enfermedades y plagas K1 Plantas - Resistencia a enfermedades y plagas K1 Botrytis cinerea AB Botrytis cinerea, the causal agent of the gray mold disease, is one of the main limiting factors of horticultural crops production worldwide, consuming up to 40% of fungicides in its control. However, this fungus has been categorized by FRAC (Fungicide Resistance Action Committee) as a phytopathogen with a high risk for fungicide resistance development, a fact that has been demonstrated in our country. In addition, and according to the "farm to fork" strategy of the recent European Green Deal, the diversity of fungicides available to growers will be reduced by 50% in 2030. For this reason, alternative control tools and molecules with fungicide activity are needed to B. cinerea control. In this study, the efficacy of emerging strategies using oligonucleotides with antifungal effect has been explored. Preliminary results, obtained in in vivo assays, have shown a significantly reduction of the fungal development, demonstrating the potential of these oligonucleotides to be novel candidates to include in the different strategies of integrated control programs of the gray mold disease.This work has been funded by: AYUDAS A LA I+D+i, EN EL ÁMBITO DEL PLAN ANDALUZ DE INVESTIGACIÓN, DESARROLLO E INNOVACIÓN (PAIDI 2020). Project code: PY20_00048 YR 2023 FD 2023 LK https://hdl.handle.net/10630/27450 UL https://hdl.handle.net/10630/27450 LA eng NO Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 19 ene 2026