RT Journal Article T1 Turbulence suppression by cardiac-cycle-inspired driving of pipe flow. A1 Scarselli, Davide A1 López-Alonso, José Manuel A1 Varshney, Atul A1 Hof, Bjoern K1 Sistema cardiovascular - Propiedades mecánicas K1 Biomecánica AB Flows through pipes and channels are, in practice, almost always turbulent, and the multiscale eddying motion is responsible for a major part of the encountered friction losses and pumping costs1. Conversely, for pulsatile flows, in particular for aortic blood flow, turbulence levels remain low despite relatively large peak velocities. For aortic blood flow, high turbulence levels are intolerable as they would damage the shear-sensitive endothelial cell layer. Here we show that turbulence in ordinary pipe flow is diminished if the flow is driven in a pulsatile mode that incorporates all the key features of the cardiac waveform. At Reynolds numbers comparable to those of aortic blood flow, turbulence is largely inhibited, whereas at much higher speeds, the turbulent drag is reduced by more than 25%. This specific operation mode is more efficient when compared with steady driving, which is the present situation for virtually all fluid transport processes ranging from heating circuits to water, gas and oil pipelines. PB Nature Publishing Group UK YR 2023 FD 2023-09-06 LK https://hdl.handle.net/10630/27559 UL https://hdl.handle.net/10630/27559 LA eng NO Scarselli, D., Lopez, J.M., Varshney, A. et al. Turbulence suppression by cardiac-cycle-inspired driving of pipe flow. Nature 621, 71–74 (2023). https://doi.org/10.1038/s41586-023-06399-5 NO grant 189662962 of the Simons foundation, grant 075-15-2019-1893 de la Austrian Science Fund, y el grant I4188-N30, de Deutsche Forschungsgemeinschaft research unit FOR 2688 DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 20 ene 2026