RT Journal Article
T1 Nanoscale biocompatible structures generated from fluorinated tripodal phenylenes on gold nanoprisms
A1 García-Castro, Miguel
A1 Moscoso, Ana
A1 Sarabia-García, Francisco Ramón
A1 López-Romero, Juan Manuel
A1 Contreras-Cáceres, Rafael
A1 Díaz-Morilla, Amelia
K1 Oro
AB Modification of gold substrates with a stable, uniform and ultrathin layer of biocompatible materials is of tremendous interest for the development of bio-devices. We present the fabrication of hybrid systems consisting of triangular prism gold nanoparticles (Au@NTPs) covalently covered with tripod-shaped oligo(p-phenylenes) featuring trifluoromethyl groups. Their synthesis is accomplished using a biphenyl boronic ester as the key compound. Au@NTPs were prepared through a seedless procedure using 3-butenoic acid and benzyldimethyl ammonium chloride, and modified with aminothiol groups. Coverage of this amine-modified gold substrate with a self-assembled monolayer (SAM) of tripod-shaped molecules is carried out in ethanolic solution. The hybrid system avoids up to 70 % of protein corona formation, and allows unspecific attachment for bulky adsorbates, providing an optimal biosensing platform. Chemical composition and morphology are analyzed by transmission electron microscopy (TEM), UV-visible spectroscopy and field emission scanning electron microscopy (FESEM).
PB Wiley
YR 2022
FD 2022-03-09
LK https://hdl.handle.net/10630/29675
UL https://hdl.handle.net/10630/29675
LA eng
NO M. García-Castro, A. Moscoso, F. Sarabia, J. M. López-Romero, R. Contreras-Cáceres, A. Díaz. Nanoscale biocompatible structures generated from fluorinated tripodal phenylenes on gold nanoprisms.  ChemistryOpen 2022, 11, e202200007
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 21 ene 2026