RT Journal Article
T1 Innova 2020: A Follow-Up Study of the Fecal Microbiota of Infants Using a Novel Infant Formula between 6 Months and 12 Months of Age
A1 Plaza- Díaz, Julio
A1 Ruiz-Ojeda, Francisco Javier
A1 Morales, Javier
A1 Martin‐Masot, Rafael
A1 Climent, Eric
A1 Silva, Ángela
A1 Martínez Blanch, Juan F
A1 Enrique, María
A1 Tortajada, Maria
A1 Ramon, Daniel
A1 Alvarez, Beatriz
A1 Chenoll, Empar
A1 Gil, Ángel
K1 Microorganismos
AB The World Health Organization recommends exclusive breastfeeding until at least six months of age, with breast milk or formula being the primary food source until one year, followed by the gradual introduction of other foods. During weaning, the gut microbiota matures, and disruptions can lead to a higher incidence of infectious diseases. This study aimed to compare whether a new infant formula (INN) promotes a gut microbiota closer to that of breastfed (BF) infants from 6 to 12 months of age, compared to a standard formula (STD). The study involved 210 infants divided into three groups: one receiving INN formula, one receiving STD formula, and one exclusively breastfed. Key findings included lower Bacillota levels in the INN group at 6 months and significant differences in gut diversity between the BF/INN groups and the STD group. At 12 months, Verrucomicrobiota levels were higher in the INN and BF groups compared to the STD group. Additionally, Clostridium sensu stricto 1 levels were higher in the INN group, and calprotectin and immunoglobulin A levels varied across groups. The study suggests that the INN formula may promote a gut microbiota more similar to that of breastfed infants during the weaning period.
PB MDPI
YR 2023
FD 2023
LK https://hdl.handle.net/10630/33972
UL https://hdl.handle.net/10630/33972
LA eng
NO Plaza-Diaz J, Ruiz-Ojeda FJ, Morales J, Martín-Masot R, Climent E, Silva Á, Martinez-Blanch JF, Enrique M, Tortajada M, Ramon D, Alvarez B, Chenoll E, Gil Á. Innova 2020: A Follow-Up Study of the Fecal Microbiota of Infants Using a Novel Infant Formula between 6 Months and 12 Months of Age. Int J Mol Sci. 2023 Apr 17;24(8):7392.
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 19 ene 2026