RT Conference Proceedings
T1 RGD-dendritic structures on titanium alloy. Influence in the relationship between bone cells and the metal surface
A1 Molina, Noemí
A1 González-Luque, Ana
A1 Becerra-Ratia, José
A1 Santos-Ruiz, Leonor
A1 Vida-Pol, Yolanda
A1 Pérez-de-Inestrosa-Villatoro, Ezequiel
K1 Titanio-Aleaciones
K1 Cadera-Prótesis
K1 Rodillas-Prótesis
K1 Materiales biomédicos
AB Prosthetic implants are used in surgical procedures to replace a joint (hip or knee) allowing the functional recovery of the patient. Prostheses are usually made of titanium alloys. However, the lack of chemical and structural bond between the metal and the surrounding bone tissue causes a fail in the long term due to poor osseointegration. Titanium surface with RGD domains would positively influence the relationship between bone cells and the metal surface of the prostheses, thus promoting a better osseointegration [1]. Arginine-glycine-aspartic acid tripeptides (RGD) were conjugated to dendritic structures and used to pre-treat titanium disk. We demonstrate that dendrimer-presented tripeptides efficiently improves cell-material interaction.
YR 2019
FD 2019-09-18
LK https://hdl.handle.net/10630/18384
UL https://hdl.handle.net/10630/18384
LA eng
NO Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 21 ene 2026