RT Journal Article T1 Nervous necrosis virus (NNV) vaccination of carrier Senegalese sole (Solea senegalensis). A1 Souto, Sandra A1 Olveira, José A1 López-Vázquez, Carmen A1 Dopazo, Carlos A1 Labella Vera, Alejandro Manuel A1 Bandin, Isabel K1 Virus con ARN K1 Lenguados AB Viral encephalopathy and retinopathy (VER), caused by nervous necrosis virus (NNV), is one of the mostthreatening diseases affecting marine farmed fish, especially in early developmental stages. In addition, subclinicalinfections are commonly detected in both farmed and wild fish. In recent years numerous efforts havebeen made to achieve effective vaccines for the protection of different fish species against NNV infection.Vaccination experiments are always conducted on pathogen-free animals, but subclinically infected individualsmay respond differently to immunization. In this study, we have observed a different response betweenexperimentally-induced-NNV carrier Senegalese sole and NNV-free animals when immunized with a BEIinactivatedvaccine, whereas mock-vaccinated carrier fish behaved like the NNV-free group. PB Elsevier YR 2023 FD 2023 LK https://hdl.handle.net/10630/34412 UL https://hdl.handle.net/10630/34412 LA eng NO Sandra Souto, Jose G. Olveira, Carmen López-Vázquez, Carlos P. Dopazo, Alejandro Labella, Isabel Bandín, Nervous necrosis virus (NNV) vaccination of carrier Senegalese sole (Solea senegalensis), Aquaculture, Volume 579, 2024, 740211, ISSN 0044-8486, https://doi.org/10.1016/j.aquaculture.2023.740211. (https://www.sciencedirect.com/science/article/pii/S0044848623009857) NO This research was funded by Ministerio de Ciencia, Innovación y Universidades (MICIU), the Agencia Estatal de Investigación (AEI) and FEDER, grant number RTI2018-094687-B-C21. Dr. Sandra Souto was funded with a postdoctoral grant from Consellería de Cultura, Educación y Universidad, Xunta de Galicia (postdoctoral grant ED481D-2022/024). The authors are grateful to Stolt Sea Farm for kindly providing the fish, J. Franqueira for technical assistance and Native English School of Languages for the English revision. DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 20 ene 2026