RT Conference Proceedings
T1 New insights in the regulation of IGFPBs by PPARG2 to protect against insulin resistance in morbid obesity.
A1 Moreno Santos, Inmaculada
A1 Castellano-Castillo, Daniel
A1 Cardona-Díaz, Fernando
A1 Garrido, Lourdes
A1 García-Fuentes, Eduardo
A1 Tinahones-Madueño, Francisco José
A1 Macías-González, Manuel
K1 Obesidad
K1 Resistencia a la insulina
AB his study examines the role of PPARγ2 and IGFBPs in visceral adipose tissue of morbidly obese patients with varying insulin resistance (IR). PPARγ2 expression was lower in those with high IR, while IGFBP-2 showed protective effects in low IR cases, and IGFBP-3 correlated with severe IR. The findings highlight PPARγ2's regulatory role in adipocyte function and its potential as a therapeutic target for obesity-related metabolic complications.
YR 2012
FD 2012-06-28
LK https://hdl.handle.net/10630/37013
UL https://hdl.handle.net/10630/37013
LA eng
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 24 ene 2026