RT Journal Article
T1 Three LysM effectors of Zymoseptoria tritici collectively disarm chitin-triggered plant immunity.
A1 Tian, Hui
A1 MacKenzie, Craig
A1 Rodríguez-Moreno, Luis Gabriel
A1 Van den Berg, Grardy
A1 Chen, Hongxin
A1 Rudd, Jason
A1 Mesters, Jeroen
A1 Thomma, Bart
K1 Quitina - Efectos fisiológicos
K1 Inmunología vegetal
K1 Hongos fitopatógenos
AB Chitin is a major structural component of fungal cell walls and acts as a microbe- associated molecular pattern (MAMP) that, on recognition by a plant host, triggers the activation of immune responses. To avoid the activation of these responses, the Septoria tritici blotch (STB) pathogen of wheat, Zymoseptoria tritici, secretes LysM ef- fector proteins. Previously, the LysM effectors Mg1LysM and Mg3LysM were shown to protect fungal hyphae against host chitinases. Furthermore, Mg3LysM, but not Mg1LysM, was shown to suppress chitin-induced reactive oxygen species (ROS) pro- duction. Whereas initially a third LysM effector gene was disregarded as a presumed pseudogene, we now provide functional data to show that this gene also encodes a LysM effector, named Mgx1LysM, that is functional during wheat colonization. While Mg3LysM confers a major contribution to Z. tritici virulence, Mgx1LysM and Mg1LysM contribute to Z. tritici virulence with smaller effects. All three LysM effectors display partial functional redundancy. We furthermore demonstrate that Mgx1LysM binds chitin, suppresses the chitin-induced ROS burst, and is able to protect fungal hyphae against chitinase hydrolysis. Finally, we demonstrate that Mgx1LysM is able to un- dergo chitin-induced polymerization. Collectively, our data show that Z. tritici utilizes three LysM effectors to disarm chitin-triggered wheat immunity.
PB British Society for Plant Pathology
SN 14646722
YR 2021
FD 2021-04-01
LK https://hdl.handle.net/10630/30188
UL https://hdl.handle.net/10630/30188
LA eng
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 23 ene 2026