RT Journal Article T1 Classification of high dimensional data using LASSO ensembles A1 Urda, Daniel A1 Franco, Leonardo A1 Jerez-Aragonés, José Manuel K1 Bioinformática AB The estimation of multivariable predictors with good performance in high dimensional settings is a crucial task in biomedical contexts. Usually, solutions based on the applicationof a single machine learning model are provided while the use of ensemble methods is often overlooked within this area despitethe well-known benefits that these methods provide in terms of predictive performance. In this paper, four ensemble approaches are described using LASSO base learners to predict the vital status of a patient from RNA-Seq gene expression data. The results of the analysis carried out in a public breast invasive cancer (BRCA) dataset shows that the ensemble approaches outperform statistically significant the standard LASSO modelconsidered as baseline case. We also perform an analysis of the computational costs involved for each of the approaches,providing different usage recommendations according to the available computational power. LK http://hdl.handle.net/10630/14831 UL http://hdl.handle.net/10630/14831 LA eng NO Urda, D., Franco, L. and Jerez, J.M. (2017). Classification of high dimensional data using LASSO ensembles. Proceedings IEEE SSCI'17, Symposium Series on Computational Intelligence, Honolulu, Hawaii, U.S.A. (2017). ISBN: 978-1-5386-2726-6 NO Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 10 abr 2026