RT Conference Proceedings
T1 Whole-Genome Assembly: An Experimental Study of Computational Costs and Architectural Opportunities
A1 Espinosa García, Elena María
A1 López-Fernández, Iván
A1 Larrosa-Jiménez, Rafael
A1 Plata-González, Óscar Guillermo
K1 Genomas
K1 Bioinformática
AB Whole-genome sequencing (WGS) pro- vides a huge amount of reads from which a comple- te genome could be assembled. The recent advent of long read sequencing technologies, such as PacBio and Oxford Nanopore, and the subsequent appearance of high quality long reads (single molecule high-fidelity, or HiFi) have improved the scaffolding of the genome. However, both biology and computing communities still face great challenges in terms of computational cost. Thus, it is essential a high precision characte- rization of the methods for a correct identification of the main computing bottlenecks. This study will allow us to design new methods to mitigate compu- tational costs without losing accuracy and to adapt such methods to fully exploit new architectures that provide support to handle big amounts of data. In this paper, we experimentally study and characterize the most used whole-genome assemblers in order to design new approaches in this field.
YR 2022
FD 2022
LK https://hdl.handle.net/10630/25359
UL https://hdl.handle.net/10630/25359
LA spa
NO Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 24 ene 2026