RT Journal Article T1 Psychological profiles and prescription opioid misuse, craving, and withdrawal in people with chronic pain A1 Esteve-Zarazaga, Rosa A1 Barrado-Moreno, Victoria A1 Ramírez-Maestre, María del Carmen A1 Serrano-Ibáñez, Elena Rocío A1 De la Vega, Rocío A1 Ruiz-Párraga, Gema Teresa A1 Sainero-Tirado, Gloria A1 Fernández Baena, Mariano A1 Jensen, Mark P. A1 López-Martínez, Alicia Eva K1 Opiáceos K1 Dolor K1 Psicología AB Background. The negative consequences of prescription opioid misuse and opioid use disorder make it relevant to identify factors associated with this problem in individuals with chronic pain. This cross-sectional study aimed at identifying subgroups of people with chronic pain based on their psychological profiles, prescription opioid misuse, craving, and withdrawal.Methods. The sample comprised 185 individuals with chronic pain. We performed hierarchical cluster analysis on impulsivity, anxiety sensitivity, pain acceptance, pain intensity, opioid misuse, craving, and withdrawal.Results. The four-cluster solution was the optimal one. Misuse, craving, and anxiety sensitivity were higher among people in the Severe-problems cluster than among people in the other three clusters. Withdrawal was the highest in the High-withdrawal cluster. Impulsivity was higher among people in the Severe-problems and High-withdrawal clusters than those in the Moderate-problems and Mild-problems clusters. Pain acceptance was higher among people in the Mild-problems cluster than among people in the other three clusters. Anxiety sensitivity and misuse were higher among people in the Moderate-problems cluster than among people in the Mild-problems cluster.Conclusions. These results support that impulsivity, anxiety sensitivity, and pain acceptance are useful constructs to identify subgroups of people with chronic pain according to their level of prescription opioid misuse, craving, and withdrawal. The results of this study may help in selecting the early intervention most suitable for each of the identified profiles... PB Wiley YR 2024 FD 2024-01-08 LK https://hdl.handle.net/10630/28954 UL https://hdl.handle.net/10630/28954 LA eng NO Esteve, R., BarradoMoreno, V., Ramírez-Maestre, C., Serrano-Ibáñez, E. R., de la Vega, R., Ruiz-Párraga, G. T., SaineroTirado, G., Fernández Baena, M., Jensen, M., & López-Martínez, A. E. (2024). Psychological profiles and prescription opioid misuse, craving, and withdrawal in people with chronic pain. European Journal of Pain, 00, 1–17. https://doi. org/10.1002/ejp.2233 NO Funding for open access charge: Universidad de Málaga/CBUA. This research was supported by grants from the Spanish Ministry of Science and Innovation (PID2019-106086RB-I00), and the Regional Government of Andalusia (HUM-566; UMA20-FEDERJA-118). Rocío de la Vega's work is supported by the Spanish Ministry of Science and Innovation with a Ramon y Cajal contract (RYC2018-024722-I). DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 26 abr 2026