RT Conference Proceedings T1 RRGNNV capsid protein amino acids 247 and 270 are involved in betanodavirus virulence to European sea bass (Dicentrarchus labrax) A1 Moreno, Patricia A1 Souto, Sandra A1 Leiva-Rebollo, Rocío A1 García-Rosado, Esther A1 Borrego-García, Juan José A1 Bandín Matos, Isabel A1 Alonso-Sánchez, María del Carmen K1 Luvinas-Virus K1 Virología veterinaria K1 Microbiología AB Recombinant RGNNV viruses harbouring SJNNV-type amino acids at positions 247 and/or 270 (Mut247Dl965, Mut270Dl965,Mut247+270Dl965) were generated by reverse genetics. The effect of these modifications on viral replication was evaluated in cell culture andin infected fish. Experimental infections were also performed to analyse viral virulence and fish immune response. YR 2019 FD 2019-09-18 LK https://hdl.handle.net/10630/18383 UL https://hdl.handle.net/10630/18383 LA eng NO Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 20 ene 2026