RT Journal Article T1 Assessment of long‐term mild and major neurocognitive disorders 48 months after cardiac surgery A1 Florido Santiago, María Mercedes A1 Pérez-Belmonte, Luis Miguel A1 Lara-Muñoz, José Pablo A1 Millán-Gómez, María Mercedes A1 Pérez-Velasco, Miguel Angel A1 Osuna Sánchez, Julio A1 García-Casares, Natalia A1 Gómez-Huelgas, Ricardo A1 Blanco-Reina, Encarnación A1 Barbancho-Fernández, Miguel Ángel K1 Corazón - Cirugía K1 Demencia AB ObjectivesTo assess the incidence of both Mild and Major Neurocognitive Disorders (NCD), according to the DSM-5 criteria, after cardiac surgery (off-pump an on-pump procedures) and to propose some risk associated factors.MethodsProspective and sequential study. Patients (n = 70, 65.9 years old, mean age) were evaluated for cognitive function (Neuronorma Battery) and daily life activities (Barthel Index and Bayer-Activities of Daily Living Scale) before surgery and at 1, 6, 12, and 48 months postoperatively. Off-pump (n = 36) and on-pump (n = 34) patients groups were compared. DSM-5 criteria for Mild NCD and Major NCD were applied. Independent associated risk factors were described.ResultsA 40.8% (off-pump) and 39.3% (on-pump) of patients met DSM-5 criteria for Mild NCD 48 months after cardiac surgery and a further 7.1% (on-pump) of them, for Major NCD. Clinical factors were associated with Mild NCD and both clinical and surgical factors, were associated with Major NCD.ConclusionA relevant incidence of long-term Mild NCD and Major NCD has been described 48 months after cardiac surgery, more intense in the on-pump group of patients. Assessment (identifying those with higher risk), prevention and treatment strategies for these patients should be provided. The DSM-5 criteria to classify NCD could be applied to characterize any cognitive decline due to any disease or surgical procedure. PB Wiley YR 2025 FD 2025 LK https://hdl.handle.net/10630/40858 UL https://hdl.handle.net/10630/40858 LA eng NO Florido‐Santiago, M., Pérez‐Belmonte, L. M., Lara, J. P., Millán‐Gómez, M., Pérez‐Velasco, M. A., Osuna‐Sánchez, J., García‐Casares, N., Gómez‐Huelgas, R., Blanco‐Reina, E., & Barbancho, M. A. (2025). Assessment of long‐term mild and major neurocognitive disorders 48 months after cardiac surgery. International Journal of Geriatric Psychiatry, 40, e70175. https://doi.org/10.1002/gps.7017 NO Funding for open access charge: Universidad de Málaga / CBUA DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 12 abr 2026