RT Conference Proceedings
T1 Efficacy Of Intensive Tele-Rehabilitation Combined With Donepezil Compared To Face-to-face Administration
A1 Gómez Pérez, África Yolanda
A1 Torres-Prioris, María José
A1 Melgar Mota, Ana
A1 Hohl, Ariane
A1 Gutiérrez-Cordero, Ismael
A1 Ariza-Corbo, María José
A1 Ortega Palacios, Ricardo
A1 Alfaro Rubio, Francisco
A1 Edelkraut, Lisa
A1 Berthier-Torres, Marcelo Luis
A1 Dávila-Arias, María Guadalupe
K1 Logoterapia
K1 Lenguaje - Aspectos fisiológicos
AB Objectives: (a) To evaluate the benefits promoted by two modalities of intensive language-action therapy, telerehabilitation (Tele-ILAT) and face-to-face (ILAT), applied alone and in combination with Donepezil to persons with chronic post-stroke aphasia (PSA) (phase 1). (b) To examine the best remote or hybrid strategy to maintain the gains in language and language-affiliated behaviours (communication, psychological adjustment, and quality of life) promoted by both modalities of ILAT, and to determine the efficacy of these interventions in reducing the therapist burden (phase 2).(c) To identify potential predictors of treatment response, including gene markers, and to detect changes in language,   cognition, emotional functions and neural plasticity using multimodal MRI. Methodology: Estimated sample size: 48 participants with chronic PSA are required to obtain a power of 80% (  increment of 5 points ± 4) relative to baseline scores on the Western Aphasia Battery-Revised.Methods and design: a randomized control trial involving four groups comparing the effectiveness of ILAT applied online, and face-to-face administered alone and with Donepezil (phase 1); three quasi-randomised parallel groups (asynchronous, hybrid and control) (phase 2). Results and conclusions: Primary outcome measures: aphasia severity, communication, behaviour, and quality of life.   Evaluations will determine potential predictive variables of response, as well as brain and language changes associated with the treatments at different timepoints. This trial will determine: (a) whether Tele-ILAT administered alone and combined with Donepezil reduces aphasia severity and language-affiliated deficits in the same manner as face-to-face ILAT and the contribution of adding Donepezil to these interventions; (b) the best long-term remote maintenance-therapy.
YR 2022
FD 2022
LK https://hdl.handle.net/10630/24799
UL https://hdl.handle.net/10630/24799
LA eng
NO Se presentó el trabajo en la modalidad poster. Se trata de un artículo preliminar en desarrollo que se enmarca dentro del proyecto P20_00501 "Telerrehabilitación en afasia: evaluación de no inferioridad frente a terapia presencial e identificación de biomarcadores predictores de eficacia" (Junta de Andalucía (PAIDI 2020)).
NO Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 20 ene 2026