RT Journal Article T1 Pain Acceptance Creates an Emotional Context That Protects against the Misuse of Prescription Opioids: A Study in a Sample of Patients with Chronic Noncancer Pain. A1 Esteve-Zarazaga, Rosa A1 Marcos, Estefanía A1 Reyes-Pérez, Ángela A1 López-Martínez, Alicia Eva A1 Ramírez-Maestre, María del Carmen K1 Dolor - Aspectos psicológicos K1 Opiáceos AB There is solid evidence of an association between several psychological flexibility processes, particularly pain acceptance, and adaptation to chronic pain. However, there are relatively few studies on the relationship between pain acceptance and opioid misuse in chronic pain patients. Thus, the aim of the present study was to test a hypothetical model in which pain acceptance would regulate pain sensations and pain-related thoughts and emotions, which would be related to opioid misuse. The sample comprised 140 chronic pain patients attending two hospitals. All patients were receiving pharmacological treatment, including opioid analgesics. Structural equation modelling analyses showed a significant association between higher pain acceptance and lower pain intensity and catastrophizing, and lower levels of anxiety and depression. Only higher anxiety and depression were significantly associated with increased opioid misuse. The results suggest that levels of anxiety, depression, and pain acceptance must be assessed before opioids are prescribed. Pain acceptance implies a relationship with internal events that protects against anxiety and depression and thus against opioid misuse. Acceptance and Commitment Therapy appears to be particularly appropriate for these patients. PB MDPI YR 2021 FD 2021-03-16 LK https://hdl.handle.net/10630/28129 UL https://hdl.handle.net/10630/28129 LA eng NO Esteve, R.; Marcos, E.; Reyes-Pérez, Á.; López-Martínez, A.E.; Ramírez-Maestre, C. (2021). Pain Acceptance Creates an Emotional Context That Protects against the Misuse of Prescription Opioids: A Study in a Sample of Patients with Chronic Noncancer Pain. International Journal of Environmental Research and Public Health, 18(6), 3054. https://doi.org/10.3390/ijerph18063054 NO This study was supported by grants from the Spanish Ministry of Science and Innovation(PID2019-106086RB-I00) and the Regional Government of Andalusia (HUM-566).Partial funding for open access charge: Universidad de Málaga. DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 24 ene 2026