RT Conference Proceedings
T1 Differential antiviral activity of Porphyridium cruentum polysaccharides against VHSV and NNV infections
A1 Parra-Riofrio, Geovanna
A1 Moreno-García, Patricia
A1 Abdala-Díaz, Roberto Teófilo
A1 García-Rosado, Esther
A1 Uribe-Tapia, Eduardo
A1 Alonso-Sánchez, María del Carmen
A1 Béjar-Alvarado, Julia
K1 Polisacáridos
K1 Antivirales
AB The use of functional food can be an interesting approach to prevent viral diseases in aquaculture facilities. An increasing number of studies have suggested that marine microorganisms can be a relevant source of substances with a putative use in preventing viral diseases. In particular, the antiviral activity of polysaccharides has been widely described against infections affecting higher vertebrates. In this study, we evaluate the antiviral activity of Porphyridium cruentum polysaccharides against two fish viruses: VHSV and NNV. Two different approaches have been used: (i) treatment of cells with polysaccharides before virus inoculation and (ii) addition of polysaccharides on cells after viral inoculation. Viral multiplication in treated and non-treated cells has been measured by viral genome quantification at different times post infection (p.i.).The anti-VHSV activity of P. cruentum polysaccharides has been demonstrated, blocking viral adsorption to cellular receptor, and preventing intracellular viral replication. On the contrary, no anti-NNV activity has been detected.
YR 2021
FD 2021-09
LK https://hdl.handle.net/10630/22821
UL https://hdl.handle.net/10630/22821
LA eng
NO 20th E.A.F.P. International Conference on “Diseases of Fish and Shellfish”
NO Projects AGL2017-84644-R, from MINECO/AEI/FEDER, UE, and P18-RT-1067, from Junta de Andalucía (Regional Government). G.P. has been supported by ANID-PFCHA, National Doctoral Scholarship, 2018-No. 21180059.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 19 ene 2026