RT Journal Article T1 Mathematical modeling of cancer metabolism A1 Medina-Torres, Miguel Ángel K1 Cáncer - Metabolismo AB Systemic approaches are needed and useful for the study of the very complex issue of cancer. Modeling has a central position in these systemic approaches. Metabolic reprogramming is nowadays acknowledged as an essential hallmark of cancer. Mathematical modeling could contribute to a better understanding of cancer metabolic reprogramming and to identify new potential ways of therapeutic intervention. Herein, I review several alternative approaches to metabolic modeling and their current and future impact in oncology. YR 2018 FD 2018-10-19 LK https://hdl.handle.net/10630/16664 UL https://hdl.handle.net/10630/16664 LA eng NO Supported by grants BIO2014-56092-R (MINECO and FEDER), P12-CTS-1507 (Andalusian Government and FEDER) and funds from group BIO-267 (Andalusian Government). The “CIBER de Enfermedades Raras” is an initiative from the ISCIII (Spain). The funders had no role in the study design, data collection and analysis, decision to publish orpreparation of the manuscript. DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 20 ene 2026