RT Journal Article
T1 miRNA as biomarker in lung cancer
A1 Salcedo Lobera, Esperanza
A1 Arroyo Varela, Macarena
A1 Larrosa-Jiménez, Rafael
A1 Bautista-Moreno, Rocío
K1 Cáncer - Investigación
K1 Pulmones - Cáncer - Diagnóntico - Innovaciones tecnológicas
AB Lung cancer has a high prevalence and mortality due to its late diagnosis and limited treatment, so it is essential to find biomarkers that allow a faster diagnosis and improve the survival of these patients. In this sense, biomarkers based on miRNAs have supposed a considerable advance. miRNAs, which are small RNA sequences, can regulate gene expression, so they play an essential role not only as a diagnostic biomarker but also as a therapeutic and prognostic one. Also, miRNA biomarkers can be obtained from liquid biopsies, which are less intrusive than lung biopsies, and have better accessibil-ity, safety and repeatability, which allows using those biomarkers both for diagnosis and monitoring of patients. In this review, we highlight the importance of miRNAs and collect the existing evidence of their relationship with lung cancer.
PB Springer Nature
YR 2023
FD 2023-08-29
LK https://hdl.handle.net/10630/27774
UL https://hdl.handle.net/10630/27774
LA eng
NO Lobera, E.S., Varela, M.A., Jimenez, R.L. et al. miRNA as biomarker in lung cancer. Mol Biol Rep (2023). https://doi.org/10.1007/s11033-023-08695-9
NO Funding for open access charge: Universidad de Málaga / CBUAFunding for open access publishing: Universidad Málaga / CBUA
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 20 ene 2026