RT Journal Article T1 Ethylene signaling: simple ligand, complex regulation A1 Merchante-Berg, Catharina A1 Alonso, José M. A1 Stepanova, Anna K1 Hormonas vegetales AB The hormone ethylene plays numerous roles in plant development. In the last few years the model of ethylene signaling has evolved from an initially largely linear route to a much more complex pathway with multiple feedback loops. Identification of key transcriptional and post-transcriptional regulatory modules controlling expression and/or stability of the core pathway components revealed that ethylene perception and signaling are tightly regulated at multiple levels. This review describes the most current outlook on ethylene signal transduction and emphasizes the latest discoveries in the ethylene field that shed light on the mechanistic mode of action of the central pathway components CTR1 and EIN2, as well as on the post-transcriptional regulatory steps that modulate the signaling flow through the pathway. PB ELSEVIER YR 2013 FD 2013-10 LK https://hdl.handle.net/10630/29547 UL https://hdl.handle.net/10630/29547 LA spa NO Merchante C, Alonso JM, Stepanova AN. Ethylene signaling: simple ligand, complex regulation. Curr Opin Plant Biol. 2013 Oct;16(5):554-60. doi: 10.1016/j.pbi.2013.08.001. Epub 2013 Sep 4. PMID: 24012247. NO Work in the Alonso-Stepanova lab is supported by NSF-MCB0923727 grant to JMA and ANS, NSF-MCB1158181 grant to JMA, and a Marie Curie COFUND U-Mobility postdoctoral fellowship to CM, co-funded by the University of Málaga and the EU 7FP GA nº246550 DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 21 ene 2026