RT Journal Article T1 Squamous cell carcinoma related with dental implants. A clinical cases report. A1 Granados, Francisco A1 Santos-Ruiz, Leonor A1 Contreras, Marian A1 Mellado, José A1 Martín, Gregorio A1 Bermudo, Lucas A1 Ruiz, Francisco A1 Aguilar, Yolanda A1 Yáñez, Ignacio A1 Yáñez, Ignacio K1 Cáncer K1 Implantes dentales AB One third of all cases of head and neck carcinoma (CA) concern the oral mucosa. The use of dental implants (DI) for dental rehabilitation is widely extended. However, a few studies have reported some cases with neoplasic alterations, among the tissue surrounding implants. Our aim was to analyze possible alterations at the bone-implant interface in patients with oral squamous cell carcinoma (SCC), providing new evidence that could relate or discard a possible link between these factors. We used, for the first time, different techniques, including electron microscopy and histology, to analyze the implants surface and the surrounding tissue from four clinical cases with neoplasic alterations surrounding DI. Histologically, ample inflammatory tissue was found in direct contact with the implant surface. Surface analysis of this tissue, revealed titanium percentages. According to our study, no oncological relation with deterioration of the implant surface was found, although DI were constantly related with peri-implantitis, a chronic trauma of the oral mucosa that could involve a neoplastic factor. PB Medicina Oral S.L. SN 1989-5488 YR 2020 FD 2020-01 LK https://hdl.handle.net/10630/30526 UL https://hdl.handle.net/10630/30526 LA eng NO Granados F, Santos-Ruiz L, Contreras M, Mellado J, Martin G, Bermudo L, Ruiz F, Aguilar Y, Yáñez I. Squamous cell carcinoma related with dental implants. A clinical cases report. J Clin Exp Dent. 2020;12(1):e98-102. DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 20 ene 2026