RT Journal Article
T1 Echolalia: Paying attention to a forgotten clinical feature of primary progressive aphasia.
A1 Torres-Prioris, María José
A1 Berthier-Torres, Marcelo Luis
AB Primary progressive aphasia (PPA) variants—nonfluent-agrammatic (nfvPPA), semantic (svPPA), and logopenic (lvPPA)—exhibit diverse language impairments, with echolalia (verbal repetition) underexplored. Echolalia arises from disrupted speech-language network (PSLN) dynamics, impaired in nfvPPA and lvPPA but relatively preserved in svPPA and behavioral variant frontotemporal dementia (bvFTD).Ota et al. studied echolalia in 45 PPA patients, identifying it in 12 nfvPPA and 2 unclassified cases. Echolalia in nfvPPA was associated with younger age, impaired auditory comprehension, and preserved repetition akin to transcortical aphasias, challenging traditional diagnostic tools like the Western Aphasia Battery. Mitigated echolalia was the predominant form, linked to faulty comprehension and inhibitory control. Potential echolalia in svPPA was underestimated, as repetitive questioning was excluded.No echolalia was reported in lvPPA, likely due to methodological limitations. Functional imaging linked echolalia in nfvPPA to reduced activity in executive-control regions, triggering automatic PSLN activation. These findings underscore the need for further studies to clarify echolalia's diagnostic significance in PPA variants.
PB Wiley
YR 2021
FD 2021-01
LK https://hdl.handle.net/10630/36812
UL https://hdl.handle.net/10630/36812
LA eng
NO Torres‐Prioris, M. J., & Berthier, M. L. (2021). Echolalia: Paying attention to a forgotten clinical feature of primary progressive aphasia. European journal of neurology, 28(4).
NO https://openpolicyfinder.jisc.ac.uk/id/publication/7713
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 22 ene 2026