RT Journal Article T1 Radiation and SARS-CoV-2 effects on the microbiota, immune system and health A1 González Vidal, Alejandro A1 Mercado-Sáenz, Silvia A1 López-Díaz, Beatriz A1 Burgos-Molina, Antonio Manuel A1 González-Pedrosa, María Pilar A1 Sendra-Portero, Francisco A1 Ruiz-Gómez, Miguel José K1 Radiación - Efectos fisiológicos K1 Respuesta inmune K1 Flora intestinal K1 COVID-19 AB This study aims to review the effects of radiation and SARS-CoV-2 infection on the gut microbiota, and the relationship it forms with the immune system and body axes. The intestinal microbiota is established after birth, reaching its greatest diversity in adulthood. It can be altered by factors which will depend on the host and the microorganisms. This work reviews how radiation and SARS-CoV-2 infection impact the microbiota, along with the connections established with body axes and immune system. The gut microbiota has important implications in health due to its role in multiple metabolic, physiological, and immune functions. The interaction with non-pathogenic microorganisms is beneficial; however, can cause diseases like cancer, obesity, diabetes or intestinal bowel disease. Recently, a direct relationship between microbiota and exposure to radiation in cancer patients, SARS-CoV-2 infection or different distal diseases induced via several corporal axes have been described. Microbiota acts as an independent organ, performing physiological, metabolic and immune functions; being beneficial or harmful to host. PB National Institute of Science Communication and Policy Research YR 2025 FD 2025-11-03 LK https://hdl.handle.net/10630/40652 UL https://hdl.handle.net/10630/40652 LA eng NO González-Vidal A., Mercado-Sáenz S., López-Díaz B., Burgos-Molina A.M., González-Pedrosa M.P., Sendra-Portero F., Ruiz-Gómez M.J. Radiation and SARS-CoV-2 effects on the microbiota, immune system and health. Indian J. Exp. Biol. 2025, 63:625-633. DOI: 10.56042/ijeb.v63i08.17900 NO https://or.niscpr.res.in/index.php/IJEB/about DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 21 ene 2026