RT Journal Article T1 Chemical and Metabolic Aspects of Antimetabolite Toxins Produced by Pseudomonas syringae Pathovars A1 Arrebola-Díez, Eva María A1 Cazorla-López, Francisco Manuel A1 Pérez-García, Alejandro A1 De-Vicente-Moreno, Antonio K1 Pseudomonas syringae K1 Bacterias fitopatógenas K1 Fitotoxinas AB Pseudomonas syringae is a phytopathogenic bacterium present in a wide variety of host plants where it causes diseases with economic impact. The symptoms produced by Pseudomonas syringae include chlorosis and necrosis of plant tissues, which are caused, in part, by antimetabolite toxins. This category of toxins, which includes tabtoxin, phaseolotoxin and mangotoxin, is produced by different pathovars of Pseudomonas syringae. These toxins are small peptidic molecules that target enzymes of amino acids’ biosynthetic pathways, inhibiting their activity and interfering in the general nitrogen metabolism. A general overview of the toxins’ chemistry, biosynthesis, activity, virulence and potential applications will be reviewed in this work. PB MDPI YR 2011 FD 2011-09-03 LK https://hdl.handle.net/10630/30970 UL https://hdl.handle.net/10630/30970 LA eng NO Arrebola E, Cazorla FM, Perez-García A, de Vicente A. Chemical and metabolic aspects of antimetabolite toxins produced by Pseudomonas syringae pathovars. Toxins (Basel). 2011. 3(9):1089-110. NO This study was supported by funding from Consejería de Innovación, Ciencia y Empresa, Secretaría General de Universidades, Investigación y Tecnología, Junta de Andalucía, Spain (Proyecto de Excelencia P07-AGR-2471). DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 19 ene 2026