RT Journal Article
T1 Long-Term Effectiveness of Dietary Interventions on Inflammatory Biomarkers in Women with Breast Cancer: A Systematic Review and Meta-Analysis
A1 González-Palacios Torres, Carla
A1 Muñoz-Bravo, Carlos
A1 Puebla, Iratxe inés
A1 Castillo-Hermoso, María Ángeles
A1 Toledo, Estefanía
A1 Dierssen, Trinidad
A1 Jiménez-Moleón, José Juan
A1 Barrios-Rodríguez, Rocío
K1 Mamas -- Cáncer
K1 Dieta en enfermedades
K1 Marcadores bioquímicos
K1 Inflamación
K1 Ejercicio físico
AB Context: Improving the prognosis of breast cancer remains a challenge despitethe reduction in its mortality rates. Inflammatory parameters have been suggestedas prognostic biomarkers of cancer. A healthy diet could potentially modify thesefactors; however, to date, findings have been inconclusive.Objective: This review was conducted to estimate the strength of the associationbetween healthy dietary interventions and inflammatory markers in women withbreast cancer after a minimum 6-month follow-up.Data Sources: The following literature databases were searched: MEDLINE,Embase, Scopus, Web of Science, and the Cochrane Library.Data Extraction: Clinical trials that compared the effect of dietary interventionson the inflammatory profile of patients with breast cancer were selected. Qualitywas assessed using the Cochrane Collaboration risk-of-bias tool. Two researchersindependently selected and evaluated the quality of the studies based on eligibilitycriteria.Data Analysis: Mean differences between intervention groups and their 95% CIswere calculated using a random-effects model. The presence of heterogeneity wasanalyzed with Cochran’s Q test, and I2 was estimated. Funnel plots and Egger’stest were used to assess publication bias.Results: A total of 11 trials were included in the meta-analysis. Adherence to ahealthy diet significantly decreased C-reactive protein (CRP) levels compared withthe control group (standard mean difference =–0.17; 95% CI –0.32 to –0.02; I2 =0.00%). This result was maintained in the interventions focused on weight loss,including only patients with overweight, those incorporating physical activity,when follow-up was restricted to 6 months, and with interventions lasting at least6 months
PB OXFORD
YR 2025
FD 2025-08-14
LK https://hdl.handle.net/10630/39902
UL https://hdl.handle.net/10630/39902
LA eng
NO Carla González-Palacios Torres, Carlos Muñoz-Bravo, Iratxe Inés Puebla, María Ángeles Castillo-Hermoso, Estefanía Toledo, Trinidad Dierssen-Sotos, José Juan Jiménez-Moleón, Rocío Barrios-Rodríguez, Long-Term Effectiveness of Dietary Interventions on Inflammatory Biomarkers in Women with Breast Cancer: A Systematic Review and Meta-Analysis, Nutrition Reviews, 2025;, nuaf137, https://doi.org/10.1093/nutrit/nuaf137
NO Funding for open access charge: Universidad de Málaga / CBUA
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 25 feb 2026