RT Conference Proceedings
T1 Studying the role of the strawberry Fra protein family in the flavonoid metabolism during fruit ripening
A1 Orozco-Navarrete, Begoña
A1 Castillo-Garriga, Araceli
A1 Casañal, Ana
A1 Valpuesta-Fernández, Victoriano
A1 Merchante-Berg, Catharina
K1 Fresas
K1 Metabolitos
AB Strawberry fruits are highly valued due to their flavor, aroma and benefits forhuman health. Much of these properties are due to their content in secondarymetabolites, of which flavonoids are especially abundant. Flavonoidsbiosynthetic pathways are uncovered, yet little is known about the regulation.The strawberry Fra proteins comprise a family of homologs of the major birchpollen allergen Bet v 1. Phenotypic analyses suggest that Fras are involved incolor development in strawberries [1], a process that depends on the productionof certain flavonoids. RNAseq analysis has identified at least 10 Fra members instrawberry, all with unique expression patterns suggesting functionalspecialization. Fras are structural homologs of the PYR/PYL/RCAR ABAreceptor, and are able to bind flavonoids [2].With these antecedents, our hypothesis is that Fras are involved in theregulation of the flavonoids pathway and, as the ABA receptor, would bind aprotein interactor and a ligand to regulate a signaling route and/or act asmolecular carriers.To identify the interacting partners of Fras we are doing Y2H screens againststrawberry fruit cDNA libraries and validating the interactions found by CoIP.These interactions will shed light on the functional diversity within the Fra family.In addition, stable transgenic lines that silence and overexpress different Framembers have been developed and their study will contribute to gainknowledge on how the flavonoid pathway, and hence, the fruit ripening, isregulated in strawberry; an economically important crop but for which basicresearch is still very limited.References:[1]Muñoz, C, et al. (2010). Mol Plant, 3(1): 113–24.[2]Casañal, A, et al (2013).. J. Biol. Chem., 288(49): 35322–32.
YR 2017
FD 2017-06-20
LK http://hdl.handle.net/10630/13940
UL http://hdl.handle.net/10630/13940
LA eng
NO Es una comunicación a un Congreso Internacional de primera línea en el campo objeto de la Tesis Doctoral de Begoña Orozco
NO Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 20 ene 2026