RT Journal Article T1 Role of immersive virtual reality in motor behaviour decision-making in chronic pain patients A1 Guerra-Armas, Javier A1 Flores Cortés, Mar A1 Pineda-Galán, Consolación A1 Luque-Suárez, Alejandro A1 La Touche, Roy K1 Dolor - Tratamiento K1 Realidad virtual - Uso terapéutico K1 Enfermedades crónicas - Tratamiento K1 Trastornos motores - Tratamiento AB Primary chronic pain is a major contributor to disability worldwide, with an estimated prevalence of 20–33% of the world’s population. The high socio-economic impact of musculoskeletal pain justifies seeking an appropriate therapeutic strategy. Immersive virtual reality (VR) has been proposed as a first-line intervention for chronic musculoskeletal pain. However, the growing literature has not been accompanied by substantial progress in understanding how VR exerts its impact on the pain experience and what neurophysiological mechanisms might be involved in the clinical effectiveness of virtual reality interventions in chronic pain patients. The aim of this review is: (i) to establish the state of the art on the effects of VR on patients with chronic pain; (ii) to identify neuroplastic changes associated with chronic pain that may be targeted by VR intervention; and (iii) to propose a hypothesis on how immersive virtual reality could modify motor behavioral decision-making through an interactive experience in patients with chronic pain. PB MDPI YR 2023 FD 2023-04-05 LK https://hdl.handle.net/10630/27022 UL https://hdl.handle.net/10630/27022 LA eng NO Guerra-Armas J, Flores-Cortes M, Pineda-Galan C, Luque-Suarez A, La Touche R. Role of Immersive Virtual Reality in Motor Behaviour Decision-Making in Chronic Pain Patients. Brain Sciences. 2023; 13(4):617. https://doi.org/10.3390/brainsci13040617 NO Partial funding for open access charge: Universidad de Málaga DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 21 ene 2026