RT Journal Article T1 Brazilian Beach-Cast Seaweeds: Antioxidant, Photoprotection and Cytotoxicity Properties. A1 Barroco Harb, Talissa A1 Vega Sánchez, Julia A1 Bonomi-Barufi, José A1 Casas Arrojo, Virginia A1 Abdala-Díaz, Roberto Teófilo A1 López-Figueroa, Félix A1 Chow, Fungyi K1 Algas marinas - Brasil K1 Antioxidantes K1 Antineoplásicos K1 Fenoles K1 Productos naturales marinos K1 Algas marinas - Uso terapéutico AB The potential of seaweed extracts in cosmetic applications have increased with novel development and market. Beneficial biological properties include the ability to struggle aging and anticancer agents. This research aimed to evaluate antioxidant, photoprotective and cytotoxic properties of extracts from beach-cast seaweed species from the Brazilian coast in order to propose an appropriate use of this sustainable resource. Analysis of antioxidant capacity, UV/VIS absorption, quantification of UV photoprotectors, total content of C, N and S, development of cosmetic creams and evaluation of the cytotoxicity activity against tumoral cells lines were performed. The highest antioxidant capacity was found in extracts of brown seaweeds, followed by red seaweeds, with the lowest activity detected in the green seaweed. Same pattern was observed for phenolic compounds. The extracts did not show cytotoxicity activity against healthy human cells. Other forms of extraction and incorporation of the extract into the base creams should be evaluated, the isolation and purification of substances could increase the efficiency of the photoprotective capacity. The species were highly promising and proved to be natural sources of antioxidants and substances with cytotoxicity activity against tumoral cells; therefore, they could be exploited as functional ingredients with specific applications for different types of industries. The application of seaweed extracts in combination with other natural ingredients can help in the design of new cosmetics against the negative effects of UV radiation, in addition to having the great advantage of not presenting toxicity to health or the environment because they are biodegradable. PB Springer Nature YR 2022 FD 2022-12-15 LK https://hdl.handle.net/10630/26446 UL https://hdl.handle.net/10630/26446 LA eng NO Harb, T. B., Vega, J., Bonomi-Barufi, J., Casas, V., Abdala-Díaz, R., Figueroa, F. L., & Chow, F. (2022). Brazilian Beach-Cast Seaweeds: Antioxidant, Photoprotection and Cytotoxicity Properties. Waste and Biomass Valorization, 1-17. NO Funding for open access publishing: Universidad Málaga/CBUA. // TBH thanks to CNPq (Conselho Nacional de Desenvolvimento Científico e Tecnológico; 140144/2017-0) for financial support and PhD scholarship and CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Code 001) for funding the postgraduate program in Botany at the Institute of Bioscience and PhD sandwich scholarship (88887.368014/2019-00). FC thanks FAPESP (Fundação de Amparo à Pesquisa do Estado de São Paulo; 2018/18015-8) for financial support and CNPq for research productivity grants (303937/2015-7; 303493/2018-6). This work is part of the international research project BMBF 031B0284 (023/IVV-113816). FLF thanks the financial support by the Ministry of Sciences and Innovation (BlueMaro Project, PID2020-116136RB-I0) and by the Government of Andalusia (Facco Project - UMA18-FEDER JA-162 and NAZCA Project -P20-004589). DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 4 mar 2026