RT Conference Proceedings
T1 Response to radiation in tumor biopsies from colorectal cancer patients.
A1 Burgos-Molina, Antonio Manuel
A1 Rodríguez-García, Marta
A1 González-Vidal, Alejandro
A1 Mercado-Sáenz, Silvia
A1 Ruiz-Gómez, Miguel José
K1 Cáncer - Prevención
K1 Cáncer colorrectal
K1 Biopsia
AB Analysis of the response to radiation of tumor biopsies can provide very valuable information about the possible resistance of colorectal cancer to treatment. Resistance mechanisms involve overexpression of the CREB-KDM4B-STAT3 axis, as well as alterations in the expression of BEX1 and BTG3. It is important to highlight the increase in DNA repair and decrease in apoptosis by RAD50 and IGF-1R.New therapies based on the use of molecular response markers and new therapeutic targets that address radiation resistance would be very useful for the individualization of treatments and precision medicine.
YR 2024
FD 2024
LK https://hdl.handle.net/10630/35897
UL https://hdl.handle.net/10630/35897
LA eng
NO Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 24 ene 2026