RT Conference Proceedings T1 The gene of a GPI-anchoring protein a promising new target for the control of the cucurbit powdery mildew Podosphaera xanthii. A1 Padilla-Roji, Isabel A1 Fernández-Ortuño, Dolores A1 Pérez-García, Alejandro K1 Hongos fitopatógenos K1 Cucurbitáceas - Enfermedades y plagas AB One of the main limitations of the cucurbit crops production is the powdery mildew disease,caused by the biotrophic fungus Podosphaera xanthii. An integrated management, usingseveral strategies, is carried to control the disease but the application of fungicides is the mosteffective one. The problem is that P. xanthii has been classified by the Fungicide ResistanceAction Committee (FRAC) as a pathogen with a high risk of resistance developing, in additionof the strong restrictions on the use of phytosanitary products at a European level. For thisreason, new phytosanitary tools are necessary to allow a sustainable control of thisdevastating disease such as the use of the RNA interference (RNAi) technology. In this work,dsRNA targeting a P. xanthii gene, which encodes a protein that appears to be essential forthe correct assembly of the fungal cell wall, was evaluated. Preliminary gene silencing resultshave shown a significant reduction of fungal development on melon plants suggesting that thisgene may be a promising target for the control of powdery mildew of cucurbits.This work has been funded by AEI (PID2019-107464RB-C21). YR 2023 FD 2023 LK https://hdl.handle.net/10630/27448 UL https://hdl.handle.net/10630/27448 LA eng NO Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 21 ene 2026