RT Journal Article
T1 Fish Iridoviridae: infection, vaccination and immune response
A1 Leiva Rebollo, Rocío
A1 Labella Vera, Alejandro Manuel
A1 Gémez Mata, Juan
A1 Castro-López, María Dolores
A1 Borrego García, Juan José
K1 Iridovirus
AB Each year, due to climate change, an increasing number of new pathogens are being discovered and studied, leadingto an increase in the number of known diseases affecting various fish species in different regions of the world. Virusesfrom the family Iridoviridae, which consist of the genera Megalocytivirus, Lymphocystivirus, and Ranavirus, cause epizooticoutbreaks in farmed and wild, marine, and freshwater fish species (including ornamental fish). Diseases causedby fish viruses of the family Iridoviridae have a significant economic impact, especially in the aquaculture sector.Consequently, vaccines have been developed in recent decades, and their administration methods have improved.To date, various types of vaccines are available to control and prevent Iridoviridae infections in fish populations.Notably, two vaccines, specifically targeting Red Sea bream iridoviral disease and iridoviruses (formalin-killed vaccineand AQUAVAC® IridoV, respectively), are commercially available. In addition to exploring these themes, this reviewexamines the immune responses in fish following viral infections or vaccination procedures. In general, the evasionmechanisms observed in iridovirus infections are characterised by a systemic absence of inflammatory responsesand a reduction in the expression of genes associated with the adaptive immune response. Finally, this reviewalso explores prophylactic procedure trends in fish vaccination strategies, focusing on future advances in the field.
PB Springer Nature
YR 2024
FD 2024-07-15
LK https://hdl.handle.net/10630/33081
UL https://hdl.handle.net/10630/33081
LA eng
NO Leiva-Rebollo, R., Labella, A.M., Gémez-Mata, J. et al. Fish Iridoviridae: infection, vaccination and immune response. Vet Res 55, 88 (2024). https://doi.org/10.1186/s13567-024-01347-1
NO PCM_00059 (Proyectos de I + D + i en el marco del Plan Complementario de Ciencias Marinas)
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 26 feb 2026