RT Journal Article
T1 Bioactivity of food melanoidins is mediated by gut microbiota.
A1 Pérez-Burillo, Sergio
A1 Rajakaruna, Sumudu
A1 Pastoriza, Silvia
A1 Paliy, Oleg
A1 Rufián-Henares, José Ángel
K1 Flora intestinal - Investigación
K1 Maillard, Reacción de
AB Melanoidins are an important component of the human diet (average consumption 10g/day), which escape gastrointestinal digestion and are fermented by the gut microbiota. In this paper melanoidins from different food sources (coffee, bread, beer, balsamic vinegar, sweet wine, biscuit, chocolate, and breakfast cereals) were submitted to an in vitrodigestion and fermentation process, and their bioactivity was assessed. Some melanoidins were extensively used by gut microbes, increasing production of short chain fatty acids (mainly acetate and lactate) and favoring growth of the beneficial genera Bifidobacterium (bread crust, pilsner and black beers, chocolate and sweet wine melanoidins) andFaecalibacterium (biscuit melanoidins). Quantification of individual phenolic compounds after in vitro fermentation allowed their identification as microbial metabolites or phenolics released from the melanoidins backbone (specially pyrogallol, 2-(3,4-dihydroxyphenyl)acetic and 3-(3,4-dihydroxyphenyl)propionic acids). Our results also showed that antioxidant capacity of melanoidins is affected by gut microbiota fermentation.
PB Elsevier
YR 2020
FD 2020
LK https://hdl.handle.net/10630/32349
UL https://hdl.handle.net/10630/32349
LA eng
NO Sergio Pérez-Burillo, Sumudu Rajakaruna, Silvia Pastoriza, Oleg Paliy, José Ángel Rufián-Henares, Bioactivity of food melanoidins is mediated by gut microbiota, Food Chemistry, Volume 316, 2020, 126309, ISSN 0308-8146, https://doi.org/10.1016/j.foodchem.2020.126309
NO Política de acceso abierto tomada de: https://v2.sherpa.ac.uk/id/publication/12825
NO This study was supported by the project AGL2014-53895-R from the Spanish Ministry of Economy and Competitiveness and by the European Regional Development Fund (FEDER) and by the National Science Foundation award DBI-1335772 to OP.
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 26 feb 2026