RT Journal Article
T1 A virus-targeted plant receptor-like kinase promotes cell-to-cell spread of RNAi
A1 Rosas Díaz, 
A1 Dan, Zhanga
A1 Fan, Pengfei
A1 Liping, Wang
A1 Xue, Ding
A1 Yuli, Jiang
A1 Jiménez-Góngora, Tamara
A1 Medina-Puche, Laura
A1 Xinyan, Zhao
A1 Zhengyan, Feng
A1 Guiping, Zhang
A1 Xiaokun, Liuc
A1 Rodríguez-Bejarano, Eduardo
A1 Li, Tana
A1 Heng, Zhang
A1 Jian-Kang, Zhua
A1 Weiman, Xinga
A1 Faulkner, Christine
A1 Shingo, Nagawa
A1 Lozano Durán, Rosa
K1 Virus fitopatógenos
AB RNA interference (RNAi) in plants can move from cell to cell, allowing for systemic spread of an antiviral immune response. How this cell-to-cell spread of silencing is regulated is currently unknown. Here, we describe that the C4 protein from Tomato yellow leaf curl virus can inhibit the intercellular spread of RNAi. Using this viral protein as a probe, we have identified the receptor-like kinase (RLK) BARELY ANY MERISTEM 1 (BAM1) as a positive regulator of the cell-to-cell movement of RNAi, and determined that BAM1 and its closest homolog, BAM2, play a redundant role in this process. C4 interacts with the intracellular domain of BAM1 and BAM2 at the plasma membrane and plasmodesmata, the cytoplasmic connections between plant cells, interfering with the function of these RLKs in the cell-to-cell spread of RNAi. Our results identify BAM1 as an element required for the cell-to-cell spread of RNAi and highlight that signaling components have been coopted to play multiple functions in plants.
PB PNAS
YR 2018
FD 2018-01-23
LK https://hdl.handle.net/10630/34181
UL https://hdl.handle.net/10630/34181
LA eng
NO Tabata Rosas-Diaz, Dan Zhang, Pengfei Fan, Liping Wang, Xue Ding, Yuli Jiang, Tamara Jimenez-Gongora, Laura Medina-Puche, Xinyan Zhao, Zhengyan Feng, Guiping Zhang, Xiaokun Liu, Eduardo R. Bejarano, Li Tan, Heng Zhang, Jian-Kang Zhu, Weiman Xing, Christine Faulkner, Shingo Nagawa, and Rosa Lozano-Duran. A virus-targeted plant receptor-like kinase promotes cell-to-cell spread of RNAi. Proceedings of the National Academy of SciencesVol. 115, No. 6. doi:10.1073/pnas.171555611
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 4 mar 2026