RT Journal Article
T1 Tripod-shaped molecules: Synthesis and immobilization on Au(1 1 1) substrates.
A1 Sánchez-Molina, María
A1 Díaz-Morilla, Amelia
A1 Sauter, Eric
A1 Zharnikov, Michael
A1 López-Romero, Juan Manuel
K1 Macromoléculas
K1 Reacciones químicas orgánicas
K1 Teofilina
K1 Superficies (Tecnología) - Análisis
AB We describe design and synthesis of novel tripod-shaped molecules that are potentially capable of monomolecular assembly on noble metal substrates, maintaining, due to their rigidity and specific geometry, the orientation of the functional arm in a perpendicular fashion with respect to the substrate. Using a combination of X-ray photoelectron spectroscopy, X-ray absorption spectroscopy and atomic force microscopy, the ability of these molecules to form well-defined and densely packed self-assembled monolayers (SAMs) on Au(111) was demonstrated, with the majority of the molecules adsorbed in the predefined tripodal geometry, relying on the thiolate-gold anchors. The functionality of the respective monomolecular templates was proved by click reaction between the terminal alkyne groups of the monolayers and complementary azide-substituted substituent (theophylline), which served potentially as specific protein receptor. The resulting theophylline-terminated films were successfully tested for specific protein adsorption, verifying the validity and reliability of the presented concept, in terms of the tripod design and its "activation" by the click reaction.
YR 2018
FD 2018-11-09
LK https://hdl.handle.net/10630/29396
UL https://hdl.handle.net/10630/29396
LA eng
NO María Sánchez-Molina, Amelia Díaz, Eric Sauter, Michael Zharnikov, J. Manuel López-Romero, Tripod-shaped molecules: Synthesis and immobilization on Au(1 1 1) substrates, Applied Surface Science, Volume 470, 2019, Pages 259-268, ISSN 0169-4332, https://doi.org/10.1016/j.apsusc.2018.11.013
NO Política de acceso abierto tomada de: https://v2.sherpa.ac.uk/id/publication/11418
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 21 ene 2026