RT Journal Article
T1 Detection of Relevant Heavy Metal Concentrations in Human Placental Tissue: Relationship between the Concentrations of Hg, As, Pb and Cd and the Diet of the Pregnant Woman
A1 Molina-Mesa, Soledad
A1 Martínez-Cendán, Juan Pedro
A1 Moyano-Rubiales, Daniel
A1 Cubillas-Rodríguez, Inmaculada
A1 Molina-García, Jorge Antonio
A1 González-Mesa, Ernesto Santiago
K1 Placenta
AB Heavy metals can cross the placental barrier and reach the fetal compartment, threatening fetal development. Pregnant women can acquire these through food, drinking water, toxic habits or simply by breathing polluted air. The placenta has been described as a biomarker of maternal and fetal exposure to different toxic elements. Objectives: The main objective of this study was to test the possible existence of heavy metal deposits (Pb, As, Cd and Hg) in the placentas of women who gave birth at term in our setting, analyzing the influence of daily life and dietary habits. Methods: We studied 103 placentas, obtained by consecutive sampling, of women that delivered in the Regional Maternity Hospital of Malaga between March and June, 2021. As, Cd and Pb concentrations were analyzed using mass spectrometry techniques. Hg concentration was studied according to US EPA method 7473. Women also answered a questionnaire with epidemiological variables. Results: Detectable concentrations were found in 14.56% [As], 44.6% [Cd], 81.5% [Pb] and 100% [Hg]. [Pb] and [As] correlated significantly (Spearman’s Rho of 0.91 and <0.001), as did [Hg] and [Cd] (Spearman’s Rho 0.256, p < 0.004). The [Pb] and [AS] concentrations were significantly higher in cases of tap water consumption. [Hg] concentrations predicted the birth weight of female newborns
PB IOAP-MPDI
YR 2022
FD 2022-11-09
LK https://hdl.handle.net/10630/25886
UL https://hdl.handle.net/10630/25886
LA eng
NO Molina-Mesa, S.; Martínez-Cendán, J.P.; Moyano-Rubiales, D.; Cubillas-Rodríguez, I.; Molina-García, J.; González-Mesa, E. Detection of Relevant Heavy Metal Concentrations in Human Placental Tissue: Relationship between the Concentrations of Hg, As, Pb and Cd and the Diet of the Pregnant Woman. Int. J. Environ. Res. Public Health 2022, 19, 14731. https://doi.org/10.3390/ijerph192214731
NO This research received no external funding. This article is part of Soledad Molina-Mesa’s doctoral thesis. Partial funding for open access charge: Universidad de Málaga
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 21 ene 2026