RT Conference Proceedings
T1 Improvement of Bacillus velezensis UMAF6639 as a biocontrol agent
A1 Grifé-Ruiz, Montserrat
A1 Hierrezuelo, Jesús
A1 Vela-Corcía, David
A1 Pérez-García, Alejandro
A1 De-Vicente-Moreno, Antonio
A1 Romero-Hinojosa, Diego Francisco
K1 Bacillus (Bacteria)
K1 Control biológico
AB The need to implement sustainable agricultural models has led to the search for alternatives to dealwith different plant diseases, with the use of biocontrol agents being one of the most versatile options.A clear example of these agents are the strains belonging to the Bacillus velezensis group, Grampositivebacteria capable of colonizing the different structures of plants and synthesizing a variety ofcompounds with various activities, ranging from growth promotion to antagonism against to differentphytopathogens due to the synthesis of molecules such as lipopeptides (surfactins, fengycins anditurins) among others.Previous studies carried out in our research group have shown how the B. velezensis UMAF6639strain has a great biocontrol capacity in plants belonging to the Cucurbitaceae family, derived mainlyfrom the production of lipopeptides.The objective of this work focuses on the genetic improvement by random mutagenesis of said strainto obtain mutants with greater antimicrobial activity. Once the derivatives with the greatestantimicrobial activity have been identified, their characterization is being carried out to determine thegenetic changes that justify the increase in their biocontrol capacity, as well as the changes in theproduction profile of secondary metabolites, implementing genomic and metabolomic tools todecipher the different mechanisms responsible for the antagonistic activity of these strains.
YR 2022
FD 2022
LK https://hdl.handle.net/10630/25350
UL https://hdl.handle.net/10630/25350
LA spa
NO This work has been supported by contract 8.06/60.4086 financed by the biotechnology companyKOPPERT B.V. (The Netherlands) and Universidad de Málaga, Campus de Excelencia Internacional Andalucía Tech.
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 19 ene 2026