RT Journal Article
T1 Proposal and operational evaluation of a device for external and internal photodynamic therapy treatments
A1 Navarrete-de-Gálvez, Enrique
A1 Fonda-Pascual, Pablo
A1 Aguilera-Arjona, José
A1 Andrés-Díaz, José Ramón
A1 Navarrete De Gálvez, María
A1 Perera Mohamed, Shiran
A1 De-Gálvez-Aranda, María Victoria
K1 Fototerapia
K1 Luz - Efectos fisiológicos
AB Photodynamic therapy (PDT) light sources must match their emission spectrum with the absorption spectrum of the photosensitizer, provide precise treatment definition, deliver adequate irradiance, avoid thermal damage, and minimize treatment duration. Additionally, they should be adaptable to different photosensitizers, easy to manipulate, and cost-effective.Current LED sources are difficult to customize, rigid, and primarily designed for broad-area treatments. For localized treatments, laser technology is commonly employed.We propose a customizable and programmable LED-based device that not only meets these specifications but also addresses the limitations of current LED sources for localized treatments. It allows for the connection of a fiber optic terminal for internal treatments and can be fitted with light-diffusing devices capable of treating lesions externally or penetrating them internally. This device is an enhanced version of a previously developed source that has demonstrated efficacy in several pilot studies of photodynamic therapy.The proposed equipment shows significant potential for both medical and research applications, enabling the configuration of emission spectra on demand and the establishment of tailored treatment protocols based on the type of lesion being treated.
PB Elsevier
YR 2024
FD 2024-12-05
LK https://hdl.handle.net/10630/35942
UL https://hdl.handle.net/10630/35942
LA eng
NO Enrique Navarrete de Gálvez, Pablo Fonda Pascual, José Aguilera Arjona, José Ramón de Andrés Díaz, María Navarrete de Gálvez, Shiran Perera Mohamed, María Victoria de Gálvez Aranda, Proposal and operational evaluation of a device for external and internal photodynamic therapy treatments, Photodiagnosis and Photodynamic Therapy, Volume 51, 2025, 104440, ISSN 1572-1000, https://doi.org/10.1016/j.pdpdt.2024.104440.
NO Funding for open access charge: Universidad de Málaga / CBUA.This work has been supported by the project no. JA.B1-38-Junta de Andalucía's Own Plan Project. Project Reference: B1_2023-001. Project Organic: 08.09.20.33.28. Project Number: 00.941.075. And Universidad de Málaga/CBUA.
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 19 ene 2026