2026-05-31T13:47:01Zhttps://riuma.uma.es/rest/oai/request

oai:riuma.uma.es:10630/116602026-02-03T12:08:09Zcom_10630_2254col_10630_37959

00925njm 22002777a 4500 dc Rufián Plaza, José Sebastián author Rueda-Blanco, Javier author López-Márquez, Diego author Beuzón-López, Carmen del Rosario author Ruiz-Albert, Francisco Javier author 2016-06-27 Pseudomonas syringae is a model bacterial pathogen that penetrates the leaf to reach the plant apoplast, where it replicates causing disease. In order to do that, the pathogen must interfere and suppress a two-tiered plant defense response: PTI (PAMP-Triggered Immunity, or basal resistance) and ETI (Effector-Triggered Immunity). P. syringae uses a type III secretion system to directly deliver effector proteins inside the plant cell cytosol, many of which are known to suppress PTI, some of which are known to trigger ETI, and a handful of which are known to suppress ETI. Bacterial infection can also trigger a systemic plant defense response that protects the plant against additional pathogen attacks known as SAR (Systemic Acquired Resistance). We are particularly interested in the molecular and cellular mechanisms involved in effector-mediated defense evasion by P. syringae, in particular those involved in the suppression of ETI and SAR, and/or mediation of hormone signaling. Here we present data describing effector-mediated interference with plant immunity, by means of acetylation of a key positive regulator of local and systemic responses. Our work identifies a novel plant target for effector function, and characterizes its function. This work illustrates how analyzing the means by which a given effector interferes with its target can provide novel information regarding eukaryotic molecular mechanisms. http://hdl.handle.net/10630/11660 http://orcid.org/0000-0002-6888-3845 Bacterias patógenas A bacterial acetyltransferase targets the protein kinase ZIP1, a positive regulator of plant immunity