2026-06-01T22:19:28Zhttps://riuma.uma.es/rest/oai/request

oai:riuma.uma.es:10630/119902026-02-03T11:56:03Zcom_10630_2254col_10630_37959

New indolium fluorofores for two-photon absortion (2PA) bioimaging applications Pérez-de-Inestrosa-Villatoro, Ezequiel Benítez-Martín, Carlos Nájera-Albendín, Francisco Fotoquímica Fotobioquímica The development of organic materials with 2PA has attracted intensive attention in the past two decades [1]. In two-photon bio-imaging applications the design of the chromophore requires to have a good cross-section (σ2PA) and good biological compatibility which depends on the molecular volume and polarity [2]. In this work, we present the design, synthesis and characterization of new indolium derivatives. These compounds are easy to achieve with good yields and good photophysical properties. In addition, time-dependent density functional theory (TDDFT) has been carried out to investigate the energy level of the ground and excited state. Their spectral properties and assays performed on cultured cells, demonstrate the potential of these compounds as fluorescent probes with application in two-photon bio-imaging. 2016-09-13T08:53:37Z 2016-09-13T08:53:37Z 2016-09-13T08:53:37Z 2016 conference output http://hdl.handle.net/10630/11990 eng Vth Spanish-Portuguese Conference on Photochemistry Toledo 7-09-2016 open access by-nc-nd