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oai:riuma.uma.es:10630/135662026-02-03T11:55:38Zcom_10630_2254col_10630_37959

Perez-Wohlfeil, Esteban Torreño Tirado, Óscar Trelles-Salazar, Oswaldo Rogelio 2017-05-04T10:29:48Z 2017-05-04T10:29:48Z 2017 Pérez-Wohlfeil E., Torreno O., Trelles O. (2017) Pairwise and Incremental Multi-stage Alignment of Metagenomes: A New Proposal. In: Rojas I., Ortuño F. (eds) Bioinformatics and Biomedical Engineering. IWBBIO 2017. Lecture Notes in Computer Science, vol 10209. Springer, Cham http://hdl.handle.net/10630/13566 http://orcid.org/0000-0003-1554-8987 Traditional comparisons between metagenomes are often performed using reference databases as intermediary templates from which to obtain distance metrics. However, in order to fully exploit the potential of the information contained within metagenomes, it becomes of interest to remove any intermediate agent that is prone to introduce errors or biased results. In this work, we perform an analysis over the state of the art methods and deduce that it is necessary to employ fine-grained methods in order to assess similarity between metagenomes. In addition, we propose our developed method for accurate and fast matching of reads. eng open access by-nc-nd Genomas Pairwise and incremental multi-stage alignment of metagenomes: A new proposal conference output