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      <dc:title>Mathematical modeling of cancer metabolism</dc:title>
      <dc:creator>Medina-Torres, Miguel Ángel</dc:creator>
      <dc:subject>Cáncer - Metabolismo</dc:subject>
      <dc:description>Systemic approaches are needed and useful for the study of the very complex issue of cancer. Modeling has a central position in these systemic approaches. Metabolic reprogramming is nowadays acknowledged as an essential hallmark of cancer. Mathematical modeling could contribute to a better understanding of cancer metabolic reprogramming and to identify new potential ways of therapeutic intervention. Herein, I review several alternative approaches to metabolic modeling and their current and future impact in oncology.</dc:description>
      <dc:date>2018-10-19T09:53:16Z</dc:date>
      <dc:date>2018-10-19T09:53:16Z</dc:date>
      <dc:date>2018</dc:date>
      <dc:date>2018-10-19</dc:date>
      <dc:type>journal article</dc:type>
      <dc:identifier>https://hdl.handle.net/10630/16664</dc:identifier>
      <dc:identifier>10.1016/j.critrevonc.2018.02.004</dc:identifier>
      <dc:language>eng</dc:language>
      <dc:rights>http://creativecommons.org/licenses/by-nc-nd/4.0/</dc:rights>
      <dc:rights>open access</dc:rights>
      <dc:rights>Attribution-NonCommercial-NoDerivatives 4.0 Internacional</dc:rights>
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