2026-05-28T19:16:31Zhttps://riuma.uma.es/rest/oai/requestoai:riuma.uma.es:10630/186542026-02-03T12:06:22Zcom_10630_2254col_10630_37959
RIUMA. Repositorio Institucional de la Universidad de Málaga
author
Pérez-de-Inestrosa-Villatoro, Ezequiel
author
Vida-Pol, Yolanda
author
Molina, Noemi
author
Morgado, Anjara
author
Nájera-Albendín, Francisco
2019-10-28T11:26:24Z
2019-10-28T11:26:24Z
2019-10-28
https://hdl.handle.net/10630/18654
Specific cell interactions of surfaces grafted dendrimers have been applied to the study of cell adhesion. We have studied also the application of dendrimer-based uneven nanopatterns to evaluate the local RGD surface density effects on cell adhesion, as bioactive substrates to evaluate the impact of the RGD local surface density on the chondrogenic induction of adult human mesenchymal stem cells. Dendrimers that are modified through their peripheral groups have been employed for many biomedical purposes.
IgE detection via specific interactions with synthetic Dendrimeric Antigens (DeAn) is also one of the objectives that have given more attention in our group. In this way, we have been developing different methodologies for the detection of immunoglobulins, as an in vitro method for the diagnosis of allergic reactions to drugs.
We have required the development of new dendrimeric models for the study and application of these biomerdical areas. We have developed a new approach for the production of all-aliphatic polyamide dendrimers by iterative 3, 3′-diaminopivalic acid connections as building blocks for dendrimer construction. These dendrimers were studied in explicit solvent by atomistic forcefield-based molecular dynamics to characterize structural properties such as shape, radius and monomer distribution.
eng
Dendrímeros
Biomedicina - Investigación
Syntehsis and use of dendrimeric structures as a tool in biomedicine
conference output
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URL
https://riuma.uma.es/bitstreams/0a0069c0-605c-4079-9504-bebd28b4f026/download
File
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ca015904b806253067ccf24ca68d5a8c
37603
application/pdf
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